The Random Show — Biohacking, Tim’s COVID Experience, Holiday Gift Ideas, Favorite New Apps, Bad Science, Quarantine Delights, and a Small Dose of NFTs and DAOs (#549)

Illustration via 99designs

Technologist, serial entrepreneur, world-class investor, self-experimenter, and all-around wild and crazy guy Kevin Rose (@KevinRose) rejoins me for another episode of The Random Show.

In this one we discuss the recent KevKev and TimTim reunion in Marfa, good television for anyone passing time in quarantine, Kevin’s latest biohacking adventures, utility NFTs (including Kevin’s upcoming PROOF drop), donating cryptocurrency for psychedelic research, ketamine therapy, my COVID experience, holiday gifts, financing and budgeting apps, and much more.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Stitcher, Castbox, Google Podcasts, Amazon Musicor on your favorite podcast platform. You can watch the conversation on YouTube here.

Brought to you by Tonal smart home gym, LinkedIn Jobs recruitment platform with 770M users, and Helix Sleep premium mattresses. More on all three below.

The transcript of this episode can be found here. Transcripts of all episodes can be found here.

#549: The Random Show — Biohacking, Tim’s COVID Experience, Holiday Gift Ideas, Favorite New Apps, Bad Science, Quarantine Delights, and a Small Dose of NFTs and DAOs

This episode is brought to you by Tonal! Tonal is the world’s most intelligent home gym and personal trainer. It is precision engineered and designed to be the most advanced strength studio on the market today. Tonal uses breakthrough technology—like adaptive digital weights and AI learning—together with the best experts in resistance training so you get stronger, faster. Every program is personalized to your body using AI, and smart features check your form in real time, just like a personal trainer.

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What was your favorite quote or lesson from this episode? Please let me know in the comments.


Want to hear another Random Show? Listen to my most recent conversation with Kevin Rose, in which we discussed the evolving war against elevated blood glucose, recent bad decisions, workouts for the aging, how to avoid getting swindled in the NFT Wild West, emergency preparedness, riding the emotional roller coaster of investment, perceptions of clean vs. “dirty” crypto, DeFi regulation, dollar-cost averaging, tips for better sleep, keeping stress in check, and much more.

#527: The Random Show — Life-Extension Misadventures, Blockchain/Crypto Investing, NFT Experiments, Dogecoin, Zen Buddhism, and Weathering Sharp Elbows
  • Connect with Kevin Rose:

Website | PROOF | Modern Finance | Instagram | Twitter


  • How did generative art bring Kevin and me to Marfa, Texas recently, and when was the last time we really got to hang out? [05:59]
  • What have we been drinking? [10:41]
  • Kevin and his best friend Toaster’s latest forays into biohacking. [15:54]
  • Saffron highs and the calming joy of Pym mood chews. [25:56]
  • Bad ideas for conquering COVID and good TV for anyone passing time in convalescence or in need of psychological comfort. [31:14]
  • On wine clubs in high demand, and how NFTs can be used for the purpose of membership allocation. [39:02]
  • Kevin’s own utility NFT announcement, and why he’s devoting so much of his time to the NFT space these days. [45:51]
  • DAO (decentralized autonomous organization) and Dilbert discourse. [49:53]
  • Kevin applies his unique superpowers to how I might best make use of utility NFTs and the wide, wild world of Web3. [52:53]
  • What’s with the adoption of .xyz domains by crypto nerds? [1:01:28]
  • How my non-profit foundation has entered the crypto world, and thoughts on once-unthinkable strides in the mainstream acceptance — from both sides of the political aisle — of psychedelic-assisted psychotherapy. [1:02:42]
  • Can at-home ketamine treatment work, and is it safe? [1:10:32]
  • My own recent experience with the dreaded COVID: from precautions taken to treatments administered to lingering effects. [1:14:41]
  • Thoughts on the vaccine’s effect on fertility, and a suggestion for anyone trying to make the right decisions around scientific unknowns. [1:43:23]
  • Holiday gifts. [1:49:15]
  • Kevin’s financing and budgeting tools. [1:56:10]
  • Parting thoughts. [2:02:21]


MEDICAL DISCLAIMER: I’m not a doctor, nor do I play one on the Internet. Speak with a medical professional before doing anything medical-related.

FINANCIAL DISCLAIMER: I am not an investment adviser. Nor is Kevin Rose. All opinions are mine alone. Or his. There are risks involved in placing any investment in securities or in Bitcoin or in cryptocurrencies or in anything. None of the information presented herein is intended to form the basis of any offer or recommendation or have any regard to the investment objectives, financial situation, or needs of any specific person, and that includes you, my dear listener or reader. Everything you’re going to hear is for informational entertainment purposes only.

The Tim Ferriss Show is one of the most popular podcasts in the world with more than 700 million downloads. It has been selected for "Best of Apple Podcasts" three times, it is often the #1 interview podcast across all of Apple Podcasts, and it's been ranked #1 out of 400,000+ podcasts on many occasions. To listen to any of the past episodes for free, check out this page.

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12 Replies to “The Random Show — Biohacking, Tim’s COVID Experience, Holiday Gift Ideas, Favorite New Apps, Bad Science, Quarantine Delights, and a Small Dose of NFTs and DAOs (#549)”

  1. Love the Dil Doa idea. And ownership NFTs info. If you haven’t heard about it, you should look at what Mila Kunis and Ashton Kutcher are doing with cartoons and in this space. Pretty cool!

  2. @Tim it’s off topic completely.

    What do you say a person who does work that she doesn’t like and has no idea how to change that and what she might like doing for a living?

    Smile, always

  3. Great show. Love hearing the hacks. Peter attia keeps coming across my radar. Can’t seem to find his office location in NYC? Any help appreciated.

  4. Glad to hear you are on the mend — the disinformation / sheer stupidity / haters railing against vaccine / vaccine efficacy drives me insane; your perspective is coherent and consistent with what clinicians (with a brain) promulgate (my husband is one who – by the way – worked in the trenches from March 2020 on while all the ‘misinformed’ sheltered at home…). Also, I nominated our 15 yo yorkie for the Dog Aging Project and will speak to our vet about rapamycin during her next acupuncture visit…thanks for funding this important work! And thanks for – bottom line – funding scientific inquiry. Science is the empirical, reproducible understanding of our world as we know and experience it – it is not ‘left’ or ‘right’ or ‘liberal’ or ‘conservative.’ Thanks, be well and happy holidays.

    1. That’s so cool your husband is a doctor and worked on the frontlines. Does he share any tidbits on adverse reactions? My brother is blind now (arterial rupture) and has no income now, thanks to a mandate.

  5. Hey Tim! Thank you for an amazing work. I really need your help selling my book on Amazon. What is the best way to sell my book? [Moderator: LinkedIn and Amazon links removed.]

  6. Response to Tim’s question for the writers out there: Do you agree or disagree with this? Why or why not?
    “A writer is unfair to himself when he is unable to be hard on himself.”
    — Marianne Moore
    This is so relevant to my practice and experience of writing, which is in the crowded addiction-recovery space. My short answer is yes—I do my audience disservice, and therefore myself, by failure to set the bar as high as possible in terms of relevance and understandability. Longer response—part of the value I offer is translating for people like Nora Volkow, Anna Lembke and Andrew Huberman; sadly, those who most need cutting-edge information and wisdom are least able to interpret it from the direct source. In addition to direct reader communication, I need to function as an impartial observer of that communication, a lesson from the quantum model. If I’m not objective, I’m screwed.

  7. Fantastic podcast! Regarding the budgeting apps: If you’re looking for something like YNAB, but more privacy focused, it might be worth trying out Actual Budget. It’s extremely similar to YNAB, but it has built-in end-to-end encryption. I’m still on YNAB, but I’m planning to switch to Actual next year.

  8. Another great episode guys! Feels like hanging out with old friends every time you do these. I was wondering what you think about the Gala Games company? Looks like more than just a “project” they’ve got a bunch of games in the works and one released. Generative 3D (voxel) pfp series and art by Frank Miller. P2E features on games that are actually fun in their own right. Seems to be way ahead of a lot of the other offerings out there. Would love to get your take.