The Random Show Threesome — Tim Ferriss, Kevin Rose, and Matt Mullenweg (#209)

  “Goal setting isn’t enough.” My first live podcast in New York City was recorded at the 92nd Street Y to a sold-out crowd of about 900 people. This episode comes from The Random Show segment of the evening when I took the stage with Kevin Rose and Matt Mullenweg. Kevin Rose (@KevinRose) has been …

The Magic and Power of Placebo (#194)

Erik Vance (@erikvance) is an award-winning science writer based in California and Mexico City. After working as a scientist on research projects dealing with dolphin intelligence and coastal ecology, he became an educator and then an environmental consultant. In 2005, he attended UC Santa Cruz’s famed Science Communication Program and discovered a passion for journalism. Since …

My Life Extension Pilgrimage to Easter Island (#193)

“Most good science comes only after a massive amount of failure.” – David M. Sabatini This episode was a blast. It was a tropical exploration of biology, life extension, and all good things. This included a lot of Carménère wine and good old-fashioned ball busting. I was joined by: Peter Attia, MD (@peterattiamd), who rejoins the …

Dom D'Agostino — The Power of the Ketogenic Diet (#172)

“If medicine wants to focus on prevention, there’s no better tool than nutrition.” – Dominic D’Agostino Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). …

The Random Show – New Favorite Books, Memory Training, and Bets On VR (#171)

This is not going to be a long-form interview where I dissect and deconstruct a world-class performer…at least not in the usual fashion. Instead, this is a special edition of The Random Show. I am joined by Kevin Rose (@KevinRose), serial entrepreneur, world-class investor, and all around wild and crazy guy. We discuss a wide …

EXCLUSIVE: Unpublished Material from NYT Magazine Story on Cancer Metabolism

This post is very exciting for me. It covers a subject I care deeply about (cancer), and it’s exclusive, unpublished material from a New York Times Magazine feature entitled “An Old Idea, Revived: Starve Cancer to Death.” Written by Sam Apple, this piece got a lot of attention. Now, here on this blog, you can …

Dom D'Agostino on Fasting, Ketosis, and the End of Cancer (#117)

“The FDA may see ketones as a drug. I see them as a fourth macronutrient. You have fats, proteins, and carbs. Ketones are an energy-containing molecule.” – Dom D’Agostino Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior …

The Maverick of Brain Optimization (#83)

“My lab is interested in pursuing how we can enhance cognition to improve quality of life.” – Adam Gazzaley Dr. Adam Gazzaley (@adamgazz) obtained an M.D. and a Ph.D. in Neuroscience at the Mount Sinai School of Medicine in New York, then postdoctoral training in cognitive neuroscience at UC Berkeley. He is now the director of the …

Optimizing Investing, Blood, Hormones, and Life (Podcast Double-Header: #63 and #65)

Discussing life and investing with Mark Hart and Raoul Pal. [DISCLAIMER: I’m not a doctor, nor do I play one on the Internet. Speak with a medical professional before doing anything medical-related, m’kay?] There is something here for everyone. This post details two jam-packed discussions  — one with world-renowned macro investors and investment strategists (Mark Hart and …

Human Foie Gras — A Golden Opportunity

To kick things off, what is foie gras? It can be explained with a short missive from our friend Wikipedia: The California foie gras law, California S.B. 1520, is a California State statute that prohibits the “force feed[ing of] a bird for the purpose of enlarging the bird’s liver beyond normal size”… Former Senator John …