“How do you balance the desire to live longer with the desire to perform well?” — Peter Attia, MD
This episode delves into all types of performance enhancement and tracking — optimizing blood testing, drinking “jet fuel,” training for ultra-endurance sports, consuming synthetic ketones, using metabolic chambers, extending longevity by avoiding certain types of exercise, and much more.
Peter Attia is the co-founder and current president of the Nutritional Science Initiatives (NuSI).
He is an ultra-endurance athlete, compulsive self-experimenter, and one of the most fascinating human beings I know. Peter also earned his M.D. from Stanford University and holds a B.Sc. in mechanical engineering and applied mathematics from Queen’s University in Kingston, Ontario, Canada. He resided at John Hopkins Hospital as a general surgeon, then conducted research at the National Cancer Institute under Dr. Steve Rosenberg, where Peter focused on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer.
UPDATE: People loved this episode so much that we did a follow-up episode, where Peter discussed his supplement use (and what he avoids), the top-5 blood tests you should consider, and much more. Here it is (stream below or right-click here to download):
- Listen to it on Apple Podcasts
- Listen to it on Spotify
- Stream by clicking here.
- Download as MP3 by right-clicking here and choosing “save as.”
This episode is brought to you by Onnit. Joe Rogan introduced me to Onnit, and since then, my garage has resembled a showroom. I own Onnit supplements (like chewable melatonin for jetlag and flights), maces, battle ropes (not “battle robes,” as I first heard it), kettlebells, and enough gear to ensure a lifetime of self-inflicted torture and higher performance.
This podcast is also brought to you by 99Designs, the world’s largest marketplace of graphic designers. Did you know I used 99Designs to rapid prototype the cover for The 4-Hour Body? Here are some of the impressive results.
QUESTION(S) OF THE DAY: What counter-intuitive physical “hacks” or dietary approaches have been most impactful in your life? Please let me know in the comments.
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Selected Links from the Episode
- Learn more about NuSI – The Manhattan Project of Nutrition
- Learn more about the Laura and John Arnold Foundation
- Connect with Peter Attia on Twitter
- Mistakes Were Made (But Not by Me) by Carol Tavris and Elliot Aronson
- Surely You’re Joking, Mr. Feynman! by Richard Feynman
- 10% Happier by Dan Harris
- Eating Academy – Peter Attia’s Blog
- Good Calories, Bad Calories by Gary Taubes
- Peter Attia’s obsessions on performance [11:35]
- Is hemoglobin A1C a running 3-month average of your aggregate glucose level? [16:50]
- Managing metabolic syndrome [17:15]
- What are synthetic ketones and why might people care? [19:45]
- Peter Attia’s first experience consuming synthetic ketones [24:55]
- Potential benefits or advantages of consuming synthetic ketones [28:55]
- Exploring the difference between ketoacidosis and ketosis [31:10]
- A mnemonic for the difference between exogenous and endogenous [34:40]
- Interesting results derived from tests with metabolic chambers [35:15]
- Thinking about the health complications related to blood bio-markers [41:45]
- The bio-effects of swimming from Catalina Island to Los Angeles (10 hours later) [51:05]
- Questioning fecal matter transplants [53:45]
- Challenges regarding daily cycles of testosterone and how this effects testing [46:35]
- The sloppy thinking around life extension [58:45]
- Perspectives of death avoidance, IGF-1 and growth hormone use [01:03:00]
- Heart-rate optimization for longevity [1:14:15]
- Exercise recommendations for extending life [1:21:15]
- Addressing challenges with cancer, cardiovascular disease, cerebrovascular disease and neurodegenerative disease [1:44:45]
- Rapid Fire Questions: Meditation, the most enjoyable $100 spent in recent memory, the successful and the punchable [1:31:30]
- Joe Rogan
- John D. Arnold
- Krebs Cycle
- Richard Veech
- Richard Feynman
- Dan Loeb
- John Griffin
- Dennis Calibrese
- Katharine McCormick
The Tim Ferriss Show is one of the most popular podcasts in the world with more than 800 million downloads. It has been selected for "Best of Apple Podcasts" three times, it is often the #1 interview podcast across all of Apple Podcasts, and it's been ranked #1 out of 400,000+ podcasts on many occasions. To listen to any of the past episodes for free, check out this page.