Potential Tactics for Defeating Cancer — A Toolkit in 1,000 Words

(Photo: Irina Souiki)

I’ve wanted to publish this post for years.

It will propose a few simple approaches for minimizing the occurrence of cancer.

With 19 billion capillaries in our bodies, on average, virtually 100% of us have microscopic cancers by the time we’re 70 years old, more than 40% of us by age 40. There’s a good chance you have pinhead-size cancers in your body right now. These “cancers without disease” aren’t typically a problem, as they can’t grow larger than 0.5 mm without a blood supply.

But if cancer cells get constant blood and glucose? That’s when you can end up dead.

That’s not where I want to be, and it’s not where I want you to be.

A Little Backstory…

While at the annual TED Conference in 2010, I learned that two close friends had been diagnosed with cancer. The year before, another friend had died of pancreatic cancer in his early 30’s.

This all made me furious and sad. It also made me feel helpless.

As luck would have it, TED in 2010 was abuzz about someone named Dr. William Li. His 24-minute presentation had introduced the crowd to “anti-angiogenesis therapy”: in plain English, how to starve cancers of blood. Dr. Li specializes in inhibiting cancer-specific blood-vessel growth, which ostensibly keeps abnormal growth in check. The simplest “drug” he recommended was tea. Drinking a daily blend of white tea (specifically Dragon Pearl jasmine) and green tea (Japanese sencha).

I started drinking the cocktail immediately, but it was just a first step…

In clinical trials, you see, anti-angiogenesis has been largely been unsuccessful. The father of the field, Judah Folkman, was brilliant, but his brainchild (Avastin) has been a disappointment. For about $100,000 a year of Avastin, one might extend lifespan by a month or so.

So, while I kept drinking my tea, I realized it probably wasn’t enough by itself. That said, it pointed me to new research.

I, for one, believe there are systemic causes of cancer with systemic treatments. This belief began with metformin experimentation in college (not recommended without doctor supervision), followed by reading the work and references of Gary Taubes, all of which has been reinforced by conversations with oncologists over the last decade.

All trails have led back to blood and glucose.

It’s also important to realize that killing cancer cells isn’t hard. Doctors have known how to do this for 100+ years. The real questions is: how do you exploit a weakness in cancer that is NOT a weakness in normal cells? Killing cancer is easy. Killing cancer while not killing non-cancer has proven almost impossible.

The below guest post is written by Peter Attia, M.D.. It explores a simple theory of cancer growth, which simultaneously shows how you can minimize it.

Peter is the President of the Nutrition Science Initiative (NuSI). Peter spent five years at the Johns Hopkins Hospital as a general surgery resident, where he was the recipient of several prestigious awards and the author of a comprehensive review of general surgery. Peter also spent two years at the National Institutes of Health as a surgical oncology fellow at the National Cancer Institute under Dr. Steve Rosenberg, where his research focused on the role of regulatory T cells in cancer regression and other immune-based therapies for cancer. Peter earned his M.D. from Stanford University and holds a B.Sc. in mechanical engineering and applied mathematics from Queen’s University in Kingston, Ontario, Canada.

This post is designed to allow you to skim…or go deep. Here are the options:

  • The quickie (10-15 min) – Read the post but ignore footnotes. Definitely a good start if you’re in a rush.
  • The weekend warrior (30 minutes) – Read the post and footnotes, which provide an excellent intro to the science.
  • The semi-pro (60 minutes) – Read the post, footnotes, and at least one top-10 suggested articles. This will give you more of a plan and put you ahead of 90% of the people who discuss cancer.

Enter Pete

One night Tim and I were having dinner and the topic of cancer came up.

Personally and professionally, I have a great interest in cancer, so when Tim asked if I could write something about cancer that was: (i) interesting to a broad audience, (ii) not technically over the top, (iii) not my typical 5,000 word dissertation, (iv) yet nuanced enough for his readers, I agreed to give it a shot, in about 1,000 words.

(Before reading this post, you may find some value in first reading a previous post which sets up the context for this one.)

So here it is, in roughly 1,000 words…

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In 1924 a scientist named Otto Warburg happened upon a counterintuitive finding.

Cancer 1 cells, even in the presence of sufficient oxygen, underwent a type of metabolism 2 cells reserved for rapid energy demand – anaerobic metabolism 3. In fact, even when cancer cells were given additional oxygen, they still defaulted into using only glucose 4 to make ATP 5 via the anaerobic pathway. This is counterintuitive because this way of making ATP is typically a last resort for cells, not a default, due to the relatively poor yield of ATP.

This observation begs a logical question: Do cancer cells do this because it’s all they can do? Or do they deliberately ‘choose’ to do this?

The first place to look is at the mitochondria 6 of the cancer cells. Though not uniformly the case, many cancers do indeed appear to have defects in their mitochondria that prevent them from carrying out oxidative phosphorylation 7.

Explanation 1

Cancer cells, like any cells undergoing constant proliferation (recall: cancer cells don’t stop proliferating when told to do so), may be optimizing for something other than energy generation. They may be optimizing for abundant access to cellular building blocks necessary to support near-endless growth. In this scenario, a cancer would prefer to rapidly shuttle glucose through itself. In the process, it generates the energy it needs, but more importantly, it gains access to lots of carbon, hydrogen, and oxygen atoms (from the breakdown of glucose). The atoms serve as the necessary input to the rate-limiting step of their survival — growth. The selection of cancer cells is based on this ability to preferentially grow by accessing as much cellular substrate as possible.

Explanation 2

Cells become cancerous because they undergo some form of genetic insult. This insult – damage to their DNA 8 – has been shown to result in the turning off of some genes 9 (those that suppress tumor growth) and/or the activation of other genes (those that promote cell growth unresponsive to normal cell-signaling). Among other things, this damage to their DNA also damages their mitochondria, rendering cancer cells unable to carry out oxidative phosphorylation. So, to survive they must undergo anaerobic metabolism to make ATP.

Whichever of these is more accurate (a discussion beyond my word count), the end result appears the same – cancer cells almost exclusively utilize glucose to make ATP without the use of their mitochondria. The point is: cancer cells have a metabolic quirk. Regardless of how much oxygen and fatty acid 10 they have access to, they preferentially use glucose to make ATP, and they do it without their mitochondria and oxygen.

So, can this be exploited to treat or even prevent cancer?

One way this quirk has been exploited for many years is in medical imaging. FDG-PET scans 11 are a useful tool for non-invasively detecting cancer in people. By exploiting the obligate glucose consumption of cancer cells, the FDG-PET scan is a powerful way to locate cancer (see figure).

Cancer Blog Images

You can probably tell where I’m leading you. What happens if we reduce the amount of glucose in the body? Could such an intervention ‘starve’ cancer cells? An insight into this came relatively recently from an unlikely place – the study of patients with type 2 diabetes.

In the past few years, three retrospective studies of patients taking a drug called metformin have shown that diabetic patients who take metformin, even when adjusted for other factors such as body weight and other medications, appear to get less cancer.

And when they do get cancer, they appear to survive longer. Why? The answer may lie in what metformin does. Metformin does many things, to be clear, but chief among them is activating an enzyme called AMP kinase, which is important in suppressing the production of glucose in the liver (the liver manufactures glucose from protein and glycerol and releases it to the rest of the body). This drug is used in patients with diabetes to reduce glucose levels and thereby reduce insulin requirement.

So, the patients taking metformin may have better cancer outcomes because their glucose levels were lower, or because such patients needed less insulin. Insulin and insulin-like growth factor (IGF-1) also appear to play an integral role in cancer growth as recently demonstrated by the observation that people with defective IGF-1 receptors appear immune to cancer. Or, it may be that activation of AMP kinase in cancer cells harms them in some other way. We don’t actually know why, but we do know that where there is smoke there is often fire. And the ‘smoke’ in this case is that a relatively innocuous drug that alters glucose levels in the body appears to interfere with cancer.

This may also explain why most animal models show that caloric restriction improves cancer outcomes. Though historically, this observation has been interpreted through the lens of less ‘food’ for cancer. A more likely explanation is that caloric restriction is often synonymous with glucose reduction, and it may be the glucose restriction per se that is keeping the cancer at bay.

Fortunately this paradigm shift in oncology – exploiting the metabolic abnormality of cancer cells – is gaining traction, and doing so with many leaders in the field.

Over a dozen clinical trials are underway right now investigating this strategy in the cancers that appear most sensitive to this metabolic effect – breast, endometrial, cervical, prostate, pancreatic, colon, and others. Some of these trials are simply trying to reproduce the metformin effect in a prospective, blinded fashion. Other trials are looking at sophisticated ways to target cancer by exploiting this metabolic abnormality, such as targeting PI3K 12 directly.

To date, no studies in humans are evaluating the therapeutic efficacy of glucose and/or insulin reduction via diet, though I suspect that will change in the coming year or two, pending outcomes of the metformin trials.

EDITOR’S NOTE:Though it might seem premature to some, let’s make this actionable. To reduce glucose, consider following a diet (way of eating, really) such as The Slow-Carb Diet, Paleo, or any diet that induces ketosis. Many of the most influential researchers in the US, in addition to following ketogenic diets, take slow-acting metformin as a preemptive measure. NOTE: This should NOT be done without medical supervision.

Influences

I’ve been absurdly blessed to study this topic at the feet of legends, and to be crystal clear, not a single thought represented here is original work emanating from my brain. I’m simply trying to reconstruct the story and make it more accessible to a broader audience. Though I trained in oncology, my research at NIH/NCI focused on the role of the immune system in combating cancer. My education in the metabolism of cancer has been formed by the writings of those below, and from frequent discussions with a subset of them who have been more than generous with their time, especially Lewis Cantley (who led the team that discovered PI3K) and Dominic D’Agostino.

• Otto Warburg

• Lewis Cantley

• Dominic D’Agostino

• Craig Thompson

• Thomas Seyfried

• Eugene Fine

• Richard Feinman (not to be confused with Richard Feynman)

• Rainer Klement

• Reuben Shaw

• Matthew Vander Heiden

• Valter Longo

Further Reading from Tim — A Top-10 List

There is a deluge of writing about cancer.

Below, I’ve suggested a top-10 list of articles as starting points. Some are for lay audiences, some are technical, but all are worth the time to read. Here you go:

Looking for articles to pass to your parents, or to read as a lay person? Read these, in this order:

1. Non-technical talk by Craig Thompson, Pres/CEO of Sloan-Kettering

2. Science piece written about cancer (for non-technical audience) by Gary Taubes

Have a little background and want the 80/20 analysis, the greatest bang for the buck? Read this:

3. Relatively non-technical review article on the Warburg Effect written by Vander Heiden, Thompson, and Cantley

Peaking on modafinil during a flight to Tokyo? Want to deep dive for a few hours? Here are three recommendations, in this order:

4. Detailed review article by Tom Seyfried

5. Review article on the role of carb restriction in the treatment and prevention of cancer

6. Talk given by author of above paper for those who prefer video

Want four bonus reads, all very good? As you wish:

7. Moderately technical review article by Shaw and Cantley

8. Clinical paper on the role of metformin in breast cancer by Ana Gonzalez-Angulo

9. Mouse study by Dom D’Agostino’s group examining role of ketogenic diet and hyperbaric oxygen on a very aggressive tumor model

10. Mechanistic study by Feinman and Fine assessing means by which acetoacetate (a ketone body) suppresses tumor growth in human cancer cell lines

Afterword by Tim

It’s my hope that this short article offers hope. Moreover, it’s intended to offer actionable directions for those dealing with cancer or fearful of it.

Note a few things:

  • I am not a doctor, nor do I play one on the Internet. Make medical decisions with medical supervision.
  • This is a 1,000-word primer and therefore simplified. It’s not incorrect, but it is not comprehensive either, as it would impossible to digest for most people. Be sure to read the “further reading” above if you’re serious.

Have you stumbled upon any novel science/treatments related to cancer? Please share in the comments below, if so, as I’d love this post to become a living resource.

Many thanks for reading this far.

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Footnotes:


  1. A collection of cells in our bodies that grow at roughly normal speeds, but that do not respond appropriately to cell signaling. In other words, while a collection of ‘normal’ cells will grow and stop growing in response to appropriate messages from hormones and signals, cancer cells have lost this property. Contrary to popular misconception, cancers cells do not grow especially fast relative to non-cancer cells. The problem is they don’t ‘know’ when to stop growing. 
  2. The process of converting the stored energy in food (chemical energy contained mostly within the bonds of carbon and hydrogen atoms) into usable energy for the body to carry out essential and non-essential work (e.g., ion transport, muscle contraction). 
  3. The process of converting the stored energy in food (chemical energy contained mostly within the bonds of carbon and hydrogen atoms) into usable energy for the body to carry out essential and non-essential work (e.g., ion transport, muscle contraction). 
  4. A very simple sugar which many carbohydrates ultimately get broken down into via digestion; glucose is a ring of 6-carbon molecules and has the potential to deliver a lot, or a little, ATP, depending on how it is metabolized. 
  5. Adenosine triphosphate, the ‘currency’ of energy used by the body. As its name suggests, this molecule has three (tri) phosphates. Energy is liberated for use when the body converts ATP to ADP (adenosine diphosphate), by cutting off one of the phosphate ions in exchange for energy. 
  6. The part of the cell where aerobic metabolism takes place. Think of a cell as a town and the mitochondria as the factory that converts the stored energy into usable energy. If food is natural gas, and usable energy is electricity, the mitochondria are the power plants. But remember, mitochondria can only work when they have enough oxygen to process glucose or fatty acids. If they don’t, the folks outside of the factory have to make due with sub-optimally broken down glucose and suboptimal byproducts. 
  7. Aerobic metabolism is the process of extracting ATP from glucose or fatty acids when the demand for ATP is not too great, which permits the process to take place with sufficient oxygen in the cell. This process is highly efficient and generates a lot of ATP (about 36 units, for example, from one molecule of glucose) and it’s easy to manage waste products (oxygen and carbon dioxide). The process of turning glucose and fatty acid into lots of ATP using oxygen is called ‘oxidative phosphorylation.’ 
  8. Deoxyribonucleic acid, to be exact, is the so-called “building block” of life. DNA is a collection of 4 subunits (called nucleotides) that, when strung together, create a code. Think of nucleotides like letters of the alphabet. The letters can be rearranged to form words, and words can be strung together to make sentences. 
  9. If nucleotides are the letters of the alphabet, and DNA is the words and sentences, genes are the books – a collection of words strung together to tell a story. Genes tell our body what to build and how to build it, among other things. In recent years, scientists have come to identify all human genes, though we still have very little idea what most genes ‘code’ for. It’s sort of like saying we’ve read all of War and Peace, but we don’t yet understand most of it. 
  10. The breakdown product of fats (either those stored in the body or those ingested directly) which can be of various lengths (number of joined carbon atoms) and structures (doubled bonds between the carbon atoms or single bonds). 
  11. (A type of ‘functional’ radiographic study, often called a ‘pet scan’ for short, used to detect cancer in patients with a suspected tumor burden (this test can’t effectively detect small amounts of cancer and only works for ‘established’ cancers). F18 is substituted for -OH on glucose molecules, making something called 2-fluoro-2-deoxy-D-glucose (FDG), an analog of glucose. This molecule is detectable by PET scanners (because of the F18) and shows which parts of the body are most preferentially using glucose. 
  12. Phosphoinositide 3-kinase, commonly called PI3K (pronounced ‘pee-eye-three-kay’), is an enzyme (technically, a family of enzymes) involved in cell growth and proliferation. Not surprisingly, these enzymes play an important role in cancer growth and survival, and cancer cells often have mutations in the gene encoding PI3K, which render PI3K even more active. PI3Ks are very important in insulin signaling, which may in part explain their role in cancer growth, as you’ll come to understand. 

The Tim Ferriss Show is one of the most popular podcasts in the world with more than one billion downloads. It has been selected for "Best of Apple Podcasts" three times, it is often the #1 interview podcast across all of Apple Podcasts, and it's been ranked #1 out of 400,000+ podcasts on many occasions. To listen to any of the past episodes for free, check out this page.

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Matti Anttila
Matti Anttila
10 years ago

Hey Tim: I very much appreciate this article on cancer. There are two more very close to the root sources for you to explore. One is WORLD WITHOUT CANCER by G. Edward Griffin, who records the discovery of the cause of and cure for the big C in the 1970s at the Sloan Kettering Institute. The research indicated cancer is similar to scurvy in that it is a nutritional deficiency. If one gets Vitamin C, one does not get scurvy. If one gets Vitamin B17, one does not get cancer. B17 unfortunately is not found in the modern diet, which, along with the many carcinogens in our diet and environment, may go some way to explaining the explosion of cancer cases in recent decades.

The other is TOMORROW’S CANCER CURES TODAY, outlining the work of a couple of dozen doctors around the world who are successfully treating cancer using … a couple of dozen different protocols.

Love, Laughter and Smiles. Matti

P.S. As a Certified Laughter Yoga Teacher, I often quote Dr. Warburg on deep breathing and its importance in health. Laughter helps to oxygenate the effectively (and in a fun way).

kapie9969
kapie9969
9 years ago
Reply to  Matti Anttila

Read Killing cancer by Jason Winters. Some very good advice. Has what I would say are the answers.

Jen Knoedl
Jen Knoedl
10 years ago

I don’t usually comment (though I read so many of your posts) but since I sent this to 2 of my friends with cancer and they were both very grateful. Thank you for always being ahead of the curve, Tim.

Corey M. Klaus
Corey M. Klaus
10 years ago

Interesting. Most of this stuff goes way over my head. However, even as a small preventative measure I found the bit about the white and green tea combo to be interesting. I’ve been an avid tea drinker for years, I believe green tea is the “elixir of life” as I once heard. I am curious as to why this gentleman believes in that certain concoction, the White tea/Jasimine pearls mix with the Sencha. From what I understood, I thought that Gyrokuro green tea was a higher brand than the Sencha. Maybe it doesn’t matter? Anyway, facinating read and my condolences to your friend. Keep up the good work!

Logan
Logan
10 years ago

Quick clarification – is Dr. Attia implying that a low-glucose diet (ketogenic I would presume) is the logical conclusion when seeking to starve the cancer cells? Interesting ketogenic diets are used for treating epilepsy and other health issues.

todd
todd
10 years ago

Excellent Information but it appears We Are some

Way to finding a cure. I believe that stress causes cancer

And the Body is reacting accordingly. An excellent example is

From Anita moorjiani – dying to be me. I believe

one way øf addressing stress is through meditation

Hana Dolgin
Hana Dolgin
10 years ago

There is a great webinar by a doctor who healed himself naturally from terminal brain, bone and blood cancer. He gives very detailed information on how he did it.

http://www.greenmedinfo.com/video/maximized-living-webinar-problem-pink

One of the things he used was turmeric, which has been studied extensively for its anti-cancer benefits, In some cases, it makes the cancer cells more sensitive to chemotherapy while protecting healthy cells.

http://www.curcuminresearch.org has many studies on the anti-cancer properties of turmeric and curcumin.

Hana Dolgin
Hana Dolgin
10 years ago
Reply to  Hana Dolgin

There is an excellent 100% organic wild turmeric supplement containing turmeric powder and oil, plus vitamins and healthy oils for more potency and absorption. http://www.Golden-Ukon.info has more information on it.

Nora
Nora
10 years ago

I used the ketogenic protocol with the direction of a naturopath. The results I had were too incredible for an oncologist to even register that his treatments had nothing to do with it. I have been in remission for 6 years. Still follow the keto protocol (moderated!)

Doug Newburg
Doug Newburg
10 years ago

There is an excellent book available on this subject with a full diet plan. I have used it myself and found it very informative and useful especially given I knew nothing about the subject. The author, Ellen Davis, has been great with advice as well. The book, The Ketogenic Diet for Treating Cancer, is well written and easy to use. Her website is also a great starting place for understanding these ideas. http://www.ketogenic-diet-resource.com

Emil Hjorth
Emil Hjorth
10 years ago

http://www.noblegarden.eu/jasmuheen-and-ganoderma

I believe that our minds and nature can cure every problem on earth, physical, psychological or spiritual.

Here is an article about ganotherapy.

Joel Alain
Joel Alain
10 years ago

I really love this era that we are living in. It seems that BLOGs, YES, BLOGS are one of the major reasons why science and medicine is advancing so fast now. 30 years ago, we had to rely on very few people (pharmaceuticals or researchers) to come out with knowledge and solutions to our health problems But now anybody that has interest in it can “chip in” and add to the conversation, help or otherwise advance our common knowledge. And people like you, Tim are the reason that we will be healthier, faster.

Gotta love technologies and the web!

Carl Borja Nelson
Carl Borja Nelson
10 years ago

My wife was diagnosed with a very aggressive strain of breast cancer (ER PR neg. HER2 pos.). Her oncologist told me that among breast cancers the only kind more aggressive are triple negative types. I have been on a search for science based strategies to extend her life, with some success.

I received Tim’s post on cancer treatment, read it and will reread it for more actionable ideas. I also posted a comment to Tim’s post and posted a reply to another comment. I asked to be notified whenever a new comment came was submitted about this post. I think the number and type of comments illustrate the challenge faced by late stage cancer survivors. Try Googling a phrase like “surviving cancer”. My last attempt I got about 39 million possible answers.

Within the many responses I’m sure there are some comments that are based on science and evidence and are worth considering using in cancer patient’s strategies. However I also saw numerous comments that brought up strategies that have been debunked by science. For example someone posted comments promoting Gerson Therapy. Dr. Michael Greger (who runs thenonprofit organization nutritionfacts.org) produced an excellent short video based on studies putting Gerson Therapy against conventional chemo. Dr. Greger is hardly a conventional doctor; he is a vegan and scours thousands of nutritional studies each year to produce brief videos bringing the usable essence of these studies through his free videos produced by his nonprofit organization, nutritionfacts.org. But the science is what it is. Gerson Therapy comes out looking pretty bad when comparing rate of survival as compared with chemo. However a late stage cancer patient, desperately looking for any ray of hope doesn’t know the science. All he knows is sincere sounding people are promoting some ideas that sound like they offer hope. So he (or she) will waste precious weeks and months of time that he can ill afford to waste chasing an oasis. He will pour hundreds or thousands of precious dollars down another illusory hole leading nowhere.

Scientific studies are based on consistently repeated patterns of cure, healing or suppression of disease, not occasional miraculous spontaneous remissions that lure the unknowing toward illusions in their desperate search for answers.

My advice to everyone looking for answers is to be careful who you believe. The cancer internet community is populated by correct science, hype, opportunists, truth, lies, sincere believers and more. The tragedy is that many desperate people with late stage cancer don’t always have their BS detectors turned on or operating properly.

Tom
Tom
10 years ago

I just looked at the website of Michael Greger, and watched the 3 min video.

Here is the link if anybody wants to check it out. http://nutritionfacts.org/video/gerson-therapy-vs-chemotherapy/

The comments below the video should also be read as they look into the context (i.e pancreatic cancer) of the study. Below is a few of the comments from the video, one of which is from Dr. Greger. I hope I do not offend the people who wrote the posts as I have just compiled and pasted them here omitting there names.

It seems like the Gerson Therapy in this study was ultimately worse than conventional medicine using Gemcitabine-based-chemotherapy.

But, remember pancreatic cancer is the hardest cancer to cure and maybe its not a good example for cancer cure using any type of conventional nor alternative medication. We must remember, once the pancreas is damaged the essential enzymes that actually helps in the treatment of all types of cancer have been diminished (trypsin and chmytrypsin: Dr. John Beard ) An overall multiple cancer study on all types of cancers should be also tested: breast cancer, lung cancer,liver cancer, etc.to establish the effects of an vegetarian, vegan or using the Gerson therapy treatment vs conventional. In this way there can be no bias and the real treatment and survival rates maybe fully and better determined towards a mutiple of cancer types.

We must remember that the survival rate of conventional medicine for cancer is only around 5-10%, because the radiation and chemotherapeutic drugs used. Chemo and radiation does kill cancer cells, but they also destroy the immune system and that may be the reason why most persons do not survival for more than a 5 year period.

I still think more studies need to be carried out to fully determine the whole impact or picture towards cancer pateinets on a plant-based-diet using the Gerson therapy or another alternative treatment vs an animal based diet using chemo and radiation and non-chemo and radiation treatment.

Dr, Greger has not done his homework. I am disappointed in this review. I expect more Dr. Greger! Are you tied to the ACI? This study was using the Gonazalez NOT the Gerson Therapy. Dr. Gonazalez has written a book outlining how the study was totally flawed. Here is a link with a summary rebuttal. http://www.dr-gonzalez.com/jco

Michael Greger M.D. N

That is why I referred to is as a “Gerson-style regime.” Thank you for passing along that link. I’ll check out his book and if I think it has merit do a follow-up video!

Micky H Corbett
Micky H Corbett
10 years ago

Since Peter has a mechanical engineering background I was wondering if anyone has looked into the mechanical side of the chemistry. It may be energetically and structurally favourable for cancer cells to use glucose / or glutamine (as one of the reviews goes into).

I have a background in material science (my PhD was in it) but also have spent over a decade in space and aerospace engineering (plasma engines). I’m familiar with the concept of multimode systems. It sounds like an alternative approach is to look at the Least Energy Principle – it sounds like cancer cells continue to exist because their structure and dynamics allow them to adapt and maintain integrity. It also sounds like they are metastable relative to “normal” cells. Can the cell structure be energised to a higher thermodynamic state that could then decay to a lower one that is easier to fight? The trick may be to make them evolve and mutate even more?

I’d like to get involved in this even if it means reading loads and loads of papers for a year. The best email to get me at is my first name (as above) at my full name with initila (as above) plus a dot and a com.

David
David
10 years ago

Tim,

I am actually rather surprised that the article by Travis M Christofferson on Robb Wolf’s website (http://robbwolf.com/2013/09/19/origin-cancer/) isn’t in your list of suggested reading. Maybe you consider it as too long?

But that specific article totally got me excited about this subject (even asked Robb that I may translate it into German and publish on my blog which he was OK with: more than 20 pages!). I then was made aware of a Prof. Dr. Kämmerer at the University of Wuerzburg in Germany who seems to be a known name in the industry for research on fighting cancer by the principles of Warburg (ketosis etc). She has written a very good book that I read and which I recommend. It’s only available in German so far but it’s in the process of being translated into English. Since fighting cancer is such an important subject to you I would suggest that you also touch base with her, for an interview, an article, whatever. I am in contact with her and feel that she has a LOT to offer to the world in terms of fighting cancer, but as most scientists with a message she needs support from influencers, like you. It would without doubt be a great thing to make her content known to a broad mass of people in the English speaking world.

Regards from Greece,

David

Ken Martin
Ken Martin
10 years ago

It is rarely one thing, and I do not downplay the importance of anaerobic glycolysis in cancer. However, exercise was not mentioned in this post, which I see as a common oversight in oncology. If one were to exercise the morning of a PETscan it would totally ruin the scan because the image would be washed out due to so much radiated fructose going to the muscles. What does this mean on a daily basis for cancer glucose consumption, particularly since glucose uptake in the muscles and liver is elevated for hours after exercise? Furthermore, many type II diabetics can get off of medication by utilizing exercise. How much does this influence getting cancer, or cancer progression?

One criticism of this recent Metformin ( http://www.ncbi.nlm.nih.gov/pubmed/24141625 ) study in prostate cancer is how many of those subjects also exercised? If they did, were their results better than Metformin, or was the combination of both the best? This highlights a common omission in oncology – the failure to record an exercise profile at the time of a diagnosis, biopsy, or other healthcare.

Why is this important? We know that exercise decreases the risk of developing cancer, and that exercise can decrease the risk of mortality form prostate cancer. Which makes the results from the following study even more interesting – tumor blood vessel improvement (rounder vessels) was significantly correlated to better survival.

http://mb.cision.com/Public/3069/9520261/82b38a3d9391d0bb.pdf

Yes, improving tumor blood flow improves survival. Contrary to inhibiting the blood supply to cancers espoused by Dr. Li. In fact, some researchers have found that anti-angiogenic therapy (choking off the blood supply) can promote metastasis – win the battle but lose the war? (second link below) Much of this can be read in the work of Rakesh Jain, it is called vascular normalizaton hypothesis, which takes Folkman in a different direction.

http://physrev.physiology.org/content/91/3/1071.long

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

http://ac.els-cdn.com/S1535610809000348/1-s2.0-S1535610809000348-main.pdf?_tid=1087184c-8ba7-11e3-a5c5-00000aacb35f&acdnat=1391303720_3785a74583fcfdb342603acfc3c7c1ab

My intuition, and what I focused on prior to chemotherapy, was to improve the blood supply to my tumors as much as possible with exercise, which was in my control. In theory, this should elicit a better ROS chemotherapy response (radiation too).

In exercised trained people more fatty acids are used for fuel and glycogen sparing occurs. How might this also affect tumor glucose consumption? Are these effects of training, combined with a caloric restriction the best way to combat cancer rather than just utilizing one strategy?

Ken Martin
Ken Martin
10 years ago
Reply to  Ken Martin

oops, meant radiated glucose for FDG PETscan.

Brad
Brad
10 years ago

What about the pilot studies that have already been performed? The Jaminets in “Perfect Health Diet” describe some pretty nasty train wrecks that have occurred when ketogenic diets have been used on cancer patients (the exception being brain cancer, which responds well).

Muiris FitzGerald
Muiris FitzGerald
10 years ago

Great articlle about treating cancer once it has become a problem. Have you written about methods of prevention such as Gerson-styled hyper nutrition and correcting the body’s ph? You may have and I missed it; I’m new to your work.

All the best to you,

Muiris FitzGerald, NYC.

Merritt
Merritt
10 years ago

Great post. I’m very interested in preventing cancer. I can add this post to my “library”. I think there is very strong connection

“cancer -> glucose levels” or just “cancer -> sugar”.

Mel
Mel
10 years ago

Tim have u heard of the Budwig Protocol. My wife is on it and doing very well.

Erich Scharf
Erich Scharf
10 years ago

I have been dealing with pre-cancer health issues. Gerson Therapy is amazing.

Max
Max
10 years ago

I will send this to my aunt.

Awesome Tim, thanks mate.

Big props from Australia.

M

Jeromy
Jeromy
10 years ago

On Friday my father was diagnosed with Lung Cancer. He has a large mass in his upper left lung. We have not been to see the Specialist yet but are anxiously awaiting to meet with them. I am just starting to research this for him so this post is very timely. We will be going to UCSD which I’m told is very good. Any advise specific to Lung Cancer (besides telling my dad not to start smoking 40 years ago) I would greatly appreciate. We are obviously very scared, its encouraging to read all of these wonderful stories though from survivors below. I know my fathers diet is currently terrible. If I can even buy time, as much as possible, I would love for him to be able to meet his grandson due in July

Philip
Philip
10 years ago
Reply to  Jeromy

Hi

I’ve never had cancer but I do know two people personally who were diagnosed and treated their illness with a herbal tea known as Essiac. google it and you’ll find a lot of positive testimonials. A Canadian nurse treated “terminal” cancer patients with this herbal blend with astounding success.

I mention this because one of the personal cases was lung cancer in a smoker friend. His only treatment (he was uninsured) was the Essiac protocol of tea drinking. It worked for him and astounded his doctor.

Bottom line – it does no harm, and it may do good. I drink it each day as a preventative.

Jeromy
Jeromy
10 years ago
Reply to  Philip

Thank you so much Phillip. I will look into this. I am open to trying anything that may help

frank
frank
10 years ago

tim there is alot more info out there. great article now check this out

http://www.amazon.com/Sugars-That-Heal-Healing-Glyconutrients/dp/0345441079

Nic V
Nic V
10 years ago

Hi!

I was just wondering whether to be an entrepreneur a university degree is necessary? Or in particular a business/ commerce degree?

If so how would it help/ is there any other way to learn the ropes?

Dave
Dave
10 years ago

Fat v Sugar

This just aired on the BBC in the UK. It has some relevance to the article and Tim’s approach in general.

Scarily it demonstrates extremes and ‘people’ are bound to take it literally…..especially since the ‘twin on sugar’ came out better!!

Long story short…..eat what we evolved to eat…simple!

Jackie J
Jackie J
10 years ago

John Hopkins was the only facility that agreed to a 15 year olds request to test his screening test for pancreatic cancer two summers ago. He also had lost someone he loved and was outraged to learn that the short time between diagnosis and death was directly linked to the fact that testing was routinely done through a process developed 60 years ago and was accurate when patients had a 2% chance of survival. Almost the same odds of detection of an autopsy! 5 minutes, 90% accuracy, 3 cents! Enjoy. (http://new.ted.com/talks/jack_andraka_a_promising_test_for_pancreatic_cancer_from_a_teenager)

Erik G.
Erik G.
10 years ago

Tim,

Let me first thank you for your experiment in the 4HWW. I am a late bloomer and just completed reading it. Dreamlines, muse, fears are all swirling in my head and for that I thank you.

Next I wanted to speak to “Have you stumbled upon any novel science/treatments related to cancer?” I ran into an interesting point of view on cancer while pursuing my current field of study computer security. “Computer Security?” your may asked well I was watching a TED event on computer security from Danny Hillis. Another video by him on TED is titled Danny Hillis: Understanding cancer through proteomics. Very interesting worth a look. The basics are how doctors diagnose cancer may be inherently flawed and offers another solution. Please take the time for your or your PA to review worth 20 min of time.

Deirdre
Deirdre
10 years ago

Something I have come across in my own search for ways to prevent cancer: salvestrols. You can find a lot of info by searching online.

Here’s an excerpt from the Canceractive website which explains the research and development of salvestrols :

‘In 2002, Gerry Potter, Professor of Medicinal Chemistry at DeMonfort University Leicester School of Pharmacy identified and outlined a nutritional rescue mechanism that linked specific compounds in some of the most common foods we eat with cancer cell death. This rescue mechanism hinged on the metabolic activity of a certain cytochrome P450 enzyme, CYP1B1.

Cytochrome P450 enzymes constitute a host of some 5,800 enzymes existing throughout nature. 57 cytochrome P450 enzymes exist in humans. They have the ability to make many toxins and drugs water soluble and thus clear them from the body. They are our natural ´detox´ mechanism.

Importantly, the CYP1B1 enzyme was found to be expressed by all cancers, regardless of oncogenic origin, while being absent from healthy tissue (Murray GI., et al; University of Aberdeen 1995). It has now been found throughout all stages of cancer and is widely regarded as a universal cancer marker. Professor Potter had originally designed a pro-drug inhibitor (abiraterone acetate for a cytochrome P450 enzyme in prostate cancer. So when Professor Burke explained about CYP1B1, he wondered if there were pro-drug inhibitors for that too. But then the CYP1B1 factor has been around in nature for thousand of years. Maybe it wasn´t bad news. Maybe it was good news.

First he started to design a pro-drug that was benign on entry to the body, that CYP1B1 would turn into a highly toxic drug and kill the cancer cell uniquely. This he called Stilserene. Laboratory testing showed it effective in 95 per cent of cases with breast cancer cells. Since healthy cells do not carry the CYP1B1 enzyme, this really was a seek and destroy, pro-drug. However, of course, this now needs to go through very lengthy clinical trials, and the drug development could take years. Since Potter was convinced it worked, and the CYP1B1 enzyme has been around for thousands of years, he wondered if the pro-drug could be something that was naturally occurring. Something that in combination with CYP1B1 could Protect and Correct.

At the same time there was an explosion in research into a natural compound called resveratrol, the compound talked about above in the context of Chris Woollams´ Rainbow Diet, and the French Paradox.

Resveratrol had already been shown to have anti-cancer properties (for example, Jang M et al 1997, and 1999) and it is a bioactive compound called a Stilbene, very close in formula to Stilserene.

And so it was found that CYP1B1 metabolizes a specific class of dietary compound that Professors Potter and Professor Dan Burke (Professor Emeritus of Pharmaceutical Metabolism), named Salvestrols.

When Salvestrols are metabolized by CYP1B1, new compounds are produced that are anti-cancer agents and actually cause apoptosis, or death, in the cancer cell.

Salvestrols are one of the main defenders in the plant kingdom. When a plant is attacked, salvestrols are produced primarily at the site of attack (the grape skin, or a plant root). They are natural anti-fungal agents and illicit the same P450 response in plant or in human situations.

So a seemingly random collection of unrelated foods produce natural compounds to ward off attacks by fungi or predators. The most notable natural compound is probably resveratrol which is produced as a defence mechanism by red grape skins. But there are many others. Although these foods contain sugars which attract the predators, they tend to be bitter.

The list of foods includes: Broccoli, cabbages, kales, savoy, brussels sprouts, cauliflower, kohlrabi, chinese leaf, spinach, chard, lettuces, watercress, green beans, broad beans, garden peas.

Artichokes (globe), red & yellow peppers, beansprouts, celery, salad rocket, avocado, pumpkins, squashes, gourds, marrows, zucchini, cucumbers, melons, gherkins.

All red fruits such as strawberries, raspberries, grapes:and plums plus blackcurrants, redcurrants, blackberries, blueberries, mulberries, cranberries, bilberries. Apples, pears, pineapples.

And herbs such as parsley, sage, rosemary, thyme, basil and mint.

In the Journal of Orthomolecular Medicine Vol 25, No. 1, 2010 (with authors Brian A. Schaefer, D.Phil.,Catherine Dooner, B.A, M. Danny Burke, Ph.D, Gerard A. Potter, Ph.D) there was a presentation of case histories involving five cancers, breast; prostate; colon; liver; and Hodgkins lymphoma. To quote the authors, Two of the cases show how rapid and dramatic the improvement can be when nutritional deficits are addressed. In each case of the five studies the patient used Salvestrols to significant effect

Modern Nutritional Deficiencies

Salvestrols operate through a highly targeted mechanism that hinges on their metabolism by the universal cancer marker CYP1B1. Most usually this simply makes up for previous nutritional deficiencies.

Unfortunately modern farming practices for example spraying fruits with pesticides reduces production of the natural defensive compounds. GMO foods will not need them, pasteurizing fruit juices decreases them, and modern diets simply do not include these common foods like cabbages and raspberries and so people lack the important phytonutrients.

These phytonutrients are all phytoalexins and are not induced in abundance until the plant comes under attack from infection or predation. If modern farming prevents the attack through spraying or GMO then the phytoalexins are simply not made.

Pro-drugs

Salvestrols operate as natural pro-drugs, completely targeted to killing diseased cancer cells while leaving the normal cells alone. Initial research indicates that this mechanism could operate both preventatively, killing off cells as they become cancerous, and therapeutically, killing off cells that are part of active disease. (i.e. Prevention and Correction).

The authors of the above paper conclude Within the context of a nutritional approach to treating cancer, this mechanism appears to significantly reduce cancer cells in the body and thus increase chances of a beneficial outcome for a cancer sufferer. It is also true that when one chooses to utilize Salvestrols in combating this disease, a broader nutritional approach will aid in the efficient operation of this rescue mechanism. Co-factors such as biotin, vitamin C, vitamin B3, magnesium and iron are all known to be important. Other nutritional components, such as fatty acids, probiotics and selenium, also play important roles.

Specifics

Resveratrol has been shown to be attacked by an enzyme unique to pre-cancerous and cancer cells to produce a toxic substance (piceatannol) which brings about cell death. The anti-cancer agent piceatonnal is caused by the cytochrome P450 enzyme CYP 1B1. (Br J Cancer, 2002; 86: 774-778).

No one is talking about a cancer ´cure´. What people are clearly saying is that there are interesting features of Salvestrols which may help to protect and correct, and this could well be the prime mechanism for how we have prevented developing cancer over thousands of years. It is still early days yet.

Conflict of Interest?

There may well be none. Salvestrols could well be the ultimate agents of Prevention and Correction. But of all the research studies it is important to point out that in some the leading researchers have developed a range of Salvestrol products that they sell. Dr. Brian Schaefer is a Director of Acquired Intelligence Inc, the Canadian and US distributor of Salvestrols. Professor Dan Burke is a shareholder of Salvestrol Natural Products, the UK developer of the salvestrol technology. Professor Gerry Potter is a shareholder of Salvestrol Natural Products, the UK developer of the salvestrol technology.

Several products are available:

Salvestrol Platinum for people with cancer; plus Salvestrol Gold for prevention, Salvestrol Professional, Salvestrol Shield plus a topical cream. Each has a points system to indicate strength and each is all natural.

Please note that salvestrol products do not contain naringenin, a compound commonly found in grapefruit, which may interact with several CYP enzymes and could therefore interfere with some drug therapies.

We are indebted forfurther contributions for this article from Brian Schaefer (www.salvestrols.com)

References

* Potter GA: The role of CYP 1B1 as a tumour suppressor enzyme. Br J Cancer, 2002; 86 (Suppl 1), S12, 2002.

* Potter GA, Patterson LH, Wanogho E, et al: The cancer preventative agent resveratrol is converted to the anticancer agent piceatonnal by the cytochrome P450 enzyme CYP 1B1. Br J Cancer, 2002; 86: 774-778.

* Potter GA, Burke DM: Salvestrols Natural Products with Tumour Selective Activity. J Ortho Med, 2006; 21, 1: 34-36.

* Tan HL, Butler, PC, Burke, MD, et al: Salvestrols: A New Perspective in Nutritional Research. J Ortho Med, 2007; 22(1): 39-47.

* Murray GI, Taylor MC, McFadyen MCE, et al: Tumor specific expression of cytochrome P450 CYP 1B1. Cancer Res, 1997; 57: 3026-3031.

* McFadyen MCE, Melvin WT, Murray GI.: Cytochrome P450 CYP1B1 activity in renal cell carcinoma. Br J Cancer, 2004; 91: 966-971.

* McFadyen MCE, Cruickshank ME, Miller ID, et al: Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. Br J Cancer, 2001; 85:2426.

* Dana-Farber Cancer Institute: Cytochrome P450 1B1 is a Universal Tumor Antigen Eliciting Cytotoxic T Cell Responses, 2007. http://www.danafarber.org/res/technology/available.asp?case_number=641&keywords=&category_id=3&category_name=Researc+Reagents

* Potter GA: The role of CYP 1B1 as a tumour suppressor enzyme. Br J Cancer, 2002; 86 (Suppl 1), S12, 2002.

* Schaefer BA, Hoon LT, Burke DM, et al: Nutrition and Cancer: Salvestrol Case Studies. J Ortho Med, 2007; 22, 4: 177-182.

* Ware WR: Nutrition and the Prevention and Treatment of Cancer: Association of Cytochrome P450 CYP1B1 With the Role of Fruit and Fruit Extracts. Integrative Cancer Therapies, 2009; 8, 1: 22-28.

* Ware WR: P450 CYP1B1 mediated fluorescent tumor markers: A potentially useful approach for photodynamic therapy, diagnosis and establishing surgical margins. Medical Hypotheses, 2009; 72: 67-70.

* Bostwick Laboratories Announces uPM3(TM) Test, First Genetic Test for Prostate Cancer. September 23, 2005. http://www.psa-rising.com/wiredbird/bostwicklabs92303.php

* Product Monograph. Zoladex 10.8 mg Goserelin/depot. Luteinizing Hormone Releasing Hormone Analog (LHRH Analog). February 24, 2009. http://www.astrazeneca.ca/documents/ProductPortfolio/ZOLADEX%20LA_PM_en.pdf

* BCCA Protocol Summary for Treatment of Hodgkins Disease with Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine May 1, 2009. http://www.bccancer.bc.ca/NR/rdonlyres/30FDD508-96AC-4555-B682-294EA3635B06/34011/LYABVDProtocol_1May09.pdf

Anubhav
Anubhav
10 years ago

The 4-Hour Life – The definitve way to cheating death, disease and living forever.

Coming to stores near you

mark
mark
10 years ago

@timferriss – You have previously done a data collection experiment on weight loss, have you considered doing data collection on those who have fought and survived cancer and what they did, how long without it, etc??

Jeromy
Jeromy
10 years ago

Does anyone else have any opinions on Essiac Tea? I did quite a bit of reading today and there are some encouraging stories. Any suggestions on where to buy the herbs? Any additional supplements to take in conjunction to help?

Victor Heredia
Victor Heredia
10 years ago

Great article Tim,

But I am suprised no mention was made of the Italian oncologist Dr. Simoncini and his use of sodium bicarbonate (baking soda).

In essence simple carbs (sugar & fried foods, flours etc) make the body acidic which then leads to disease and cancer. Of course these foods the feed the cancer cells.

Baking soda keeps the body alkaline among many other health benefits.

Please do further research on this and i recommend a follow up post. I can also provide further years of research on cancer.

Also look into The Gersom way.

I am not an authorty on cancer nor am I medical doctor but since my good friend died of stomache cancer at the age of 32 and my cousin died of cancer a few years back I have studied cancer extensively and I think you and your readers will be happy to know what my research has found.

Victor Heredia
Victor Heredia
10 years ago

following up on my comment. i noticed a few people posted that they have cancer.

So here are a few quick tips for you:

Cancer Cures & Preventions:

1) Unhealthy foods leave an acidic residue in your body. Fruits and veggies leave an alkaline residue in you body. Eat veggies.

2) Anti-cancer juice: Carrots & red apples with red cabbage. Red cabbage is higly alkaline.

3) Peppers: New Mexico has a 50% less cancer rate than any other state. This is possibly due to the high amount of hatch chili that New Mexican eat. Pepper increase your oxygen rate which is said to kill cancer cells

4) Stop drinking all processed juice and soda. Drink as much green tea as possible.

5) Lemongrass tea has been shown to cure cancer.

6) One person stated that he ate a combination of fresh ground garlis with habanero and butter on Ezequiel bread and this cure him of cancer. Its very possible.

7) Colostrum : I have not had a cold for over a day in the last 3 years since taking this product. Colostrum builds you immune system. Go buy some.

8) Baking Soda & Molasses tea. Mix 1/2 teaspoon of baking soda with 1 tablespoon of molasses and drink it 3 times a day.

You can research any of the above and will see that they have each been shown to cure and or treat cancer.

My wife has a friend that had cancer and we gave her the above info

Chris W
Chris W
10 years ago

Tim, what are your thoughts on “cheat days” in this regard? It’s all a question of numbers, of course, but I’m wondering if it’s a significant factor when the body is going in and out of ketosis.

Sandro
Sandro
10 years ago

Thanks Tim,

I always have a look into the topic cancer, because i think and feel that the “normal” way to handle it is not the right one. Thanks for the informations in the comments that food is the healing we need.

I found Dr. Simoncini who heals cancer with baking soda (highly alkalic)

http://simoncini-cancer-center.com/en/presentation

Interessting is the he lost his “Dr. Status” with his therapy. So he must be on the right way.

Ciao,

Sandro

Ck
Ck
10 years ago

I had an interesting experience after lunch today. I have never had such a low 2hr bg reading. I had a lunch of tuna, rice and about 2T of coconut oil mayonnaise. My 2 hr reading was70!!! I didn’t feel well and I thought maybe my bg was high so you can imagine my surprise. Anyway, I googled coconut oil and diabetes and found lots of info on coconut oil lowering bg. I will continue to experiment.

Daniel Campagnoli
Daniel Campagnoli
10 years ago

I’ve been looking into AMP kinase and other key metabolic molecules and pathways. Activating AMPK does appear to be good in the battle against cancer as it moves the cellular metabolism towards fatty acid oxidation and away from glucose as a fuel source which is required for the Warburg effect.

I did notice recently a potential double-edged sword effect of AMPK in the article “AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress” (Nature 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607316/ Increasing NADPH allows the cell to combat more oxidative stress, which is particularly high in cancer cells due to their deranged metabolism.

An anti-cancer effect of activating AMPK is increasing the NAD+/NADH ratio which improves oxidative phosphorylation. One journal article on this topic is “Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression” (J Clin Invest. 2013) http://www.jci.org/articles/view/64264

I’ve posted at http://danielcampagnoli.com/a-new-year-new-insights some more details on the interplay between AMPK, NAD+/NADH and NADP/NADPH.

eric
eric
10 years ago

Peter Attia is a quack.

Gary Taubes is a Quack

Anyone sighting these people has not done his research on the subject. not even remotely.

Damian Kissey
Damian Kissey
10 years ago
Reply to  eric

Thanks to all for the above posts .

A scientific review linked here http://flowingzen.com/downloads/ReviewQG4Cancer.pdf

indicates that energy arts ( chi kung or qigong ) may not only inhibit but actually cure cancer .

Carlo Mendoza
Carlo Mendoza
10 years ago

This is a great source of information not only to those who have cancer but to all people as well. Living in a modern world where everything is done fast, seems makes our body lives and be prone to sickness faster. This is an eye opener. Thank you!

Chris
Chris
10 years ago

What can I say but “thank you!” for sharing all the learnings you’ve acquired about cancer. I’m passing these on to a special friend who happens to be in such a sad state. As well to some younger friends for whom the adoption of these data will help keep the big C away.

Alex
Alex
10 years ago

Really interesting stuff, I’ve heard about this for a while but it doesn’t seem to get the research attention it deserves. Does anyone know how/where to get involved in research or jobs in this area? I’m finishing up my PharmD and would really like get involved.

Anthony Edgington
Anthony Edgington
10 years ago

As a layman I found the above to be rather heavy reading, but what I understood I found to be in llne with my own research for the most part.

What I might add however suggests a much easier aid to prevent and also to eliminate Cancer, and that is the use of Bicarbonate of Soda taken in water to which has been added Molasses. When taken in by the cancer cells the soda turns into arsenic when in Cancerous cells but not in normal cells. Sadly, I doubt you will find it easy to sell others on your method simply because the Medical Association is determined to undermine all attempts to destroy such a lucrative practise into which they have sunk millions of dollars.

Victor
Victor
10 years ago

As a follow up, yes believe it or not, but baking soda may indeed be the cure to cancer.

Baking soda will work as a prevention if not cure for cancer along with a proper/healthy diet (Slow Carb). Google this topic and you will find some facinarting research.

Kudos to the oncologist Dr. Simoncini.

Tim you need to interview this guy.

rawbert
rawbert
10 years ago

Gerson therapy includes Calorie restriction, aPlant based diet, wheat grass juice because of a form of cyanide that is activated in the presence od cancerous tissue…coffee enimas because the hemroidal artery has a direct route to the liver without too much metabolization and caffiene is absorbed causing a blood pufifier to be released…

RICK SIMPSON? Of N.O.R.M.L. Claims to have cured cancer using an essential oil derived from high potency indica.

Tumeric, spice used often in indian cuisine.

Justin
Justin
10 years ago

Peter,

Thank you for taking the time to write this post and to you Tim for featuring it on the blog. Just a simple thank you is all.

With gratitude,

Justin

henry ocansey
henry ocansey
10 years ago

Natural remedies are the best way to treat cancer. Garlic is very good and then plenty of fruits and vegetables. These natural remedies are not a secret just as how to kill cancer is not a secret to doctors.

Adam
Adam
10 years ago

As always, Tim delivers excellent and relevant content. Thanks for sharing. Have you done any personal research on ‘Fucoidan’, and its cancer-fighting properties? If you can look past the MLM product that swears by it (I won’t mention their name), it seems pretty promising and I expect it to be the next break-out superfood.

Lena
Lena
10 years ago

Tim,

How does the cheat day in the Slow Carb Diet fit into keeping glucose low?

Using the SCD I have had success in losing 17 pounds (only 85 more to go!) in the past 9 weeks which is very encouraging to me.

I have tried every diet imaginable since I was 11 years old and have always been 50 to100 pounds overweight.

As a postmenopausal woman with a family history of breast and stomach cancer, I am desperate to lose weight and to avoid cancer.

Is the cheat day dangerous? It has been so helpful in keeping me going.

Thank you for your work.

Lena

space
space
10 years ago

Extremely interesting post. Thank you so much.

I’m a scientist even if my PhD is in Law. I do believe in hard science and the added value of drugs & lab research. People believing in conspiracy theories are spending alot of negative energy on something that is not worth it…

Still, therapies based on nature’s power have for me a sound scientific base.

It would be nice if, with all necessary disclaimers, at the end of your post you added a list of natural things that are cited in the comments and you consider as having some anticancer potential.

Once again thank you so much.

devendra
devendra
10 years ago

Article is very aprciating, how cause cancer nd how it cure nd what is mechanism behind cancer,? Tim wht factor generally influenced the cardiac tumor kind of cancer, does it is treatable in earlier when it diagnosed.?

"Ivan
"Ivan
9 years ago

I was at one time a chiropractor and herbal healer. I studied many healing modalities and came to the conclusion most people do not want to do anything for themselves. They want to pay their money and let doctors do anything to them to be fixed. They have bought into the iIcan keep doing what I’m doing and get a different result because medicine has sold me on this fallacy- get surgery, take a pill

My experiences have shown me the body is an amazing thing. I tresponds to your thougths, emotions and what you do to it and feed it. Feed it well and it will do better. Identify your negative patterns and habits be deathly honest with yourself and then find ways to make a change. That is what is great about this site. Tim Ferris is encourging lifestyle change. I think the biggest factor to illness is unhappiness or dissatisfaction at some level. The tricky part is when it involves partners that you want to love but are really suppressing your real self and prreventing its expression, in my opinion.

The most important change i think to make is read about how your thoughts and emotions create illness. I suggest “Conversations with God” by Walsh and Esther Hicks books especially :Ask and it is Given” and “Sara” (free audiobook on Youtube.com)This will require effort and motivation.

Next I would recommend anyone to become a chikung practitioner. Why?

First ,Chi Kung is about becoming aware of your energy or your life force. You learn how to conserve it, balance it and then how generate it yourself. It helps you put your life and health in your hands and not be rendered helpless by diseases etc. It can aslo be an avenue to deveop other abilities like incredible strength, durability, subtler abilities like intuition precognition, clairvoyance, etc. if you so choose. I recommend Mantak Chia’s books, which are available at almost all libraries and start with simple exercises like the inner smile. He is very open and tells you exactly what path Chi Kung takes you down and how your awareness of your body and life will grow.This will require effort and motivation.

Finally, to anyone suffering any illness and looking for help quicklyin more concrete ways I would recommend Dr Shulze. His website is loaded with information about healing the body naturally. He had a program called the “Incurables program” which i helped several “incurable” people totally heal from their diseases. But a bigger suggestion of mine, even if you choose his products is identify all your addictions-cigarettes, coffee, alcohol, work, sex, food especially|(wheat, dairy,sugar) and try to eliminate them by doing what brings you joy in life or finding what brings you joy in life.I call an addiction something you can’t stop thinking about if you are not doing it.This will require effort and motivation.

I hope this might help or guide some of you to health

Tim M
Tim M
9 years ago

Hi Tim, I actually heard a pretty interesting conversation on the radio discussing the use of the herpes virus to attack cancer cells. A company called Virttu I believe is developing this drug. The herpes virus is genetically modified. This genetic modification has removed a protein from the herpes virus. This protein typically allows the virus to beat a normal cells defenses and replicate. with this protein missing from the herpes virus a normal cell can prevent its replication. but in a cancer cell this normal self defense is gone and the herpes virus can replicate and cause lysis within the cancer cells and only the cancer cells. I heard it could be used in multiple instances with a particular cancers standard of care.

I’m not sure where the company is at with this drug but I wanted to share this because it was pretty interesting I hopefully It can help someone maybe looking for more information or an alternate possible way of treatment.

saeed
saeed
9 years ago

Hi I enjoyed reading the article above.

We have an oncologist friend who told of a one of her friends in Scotland who had been given up on and only had a short period left to live but went to a doctor who was able to administer mistletoe extract that made her tumours shrink and for her to gain back her weight to a healthy level so that she was able to live a healthy and active life for over a year before she died.

Perhaps more research could be done on this, the doctor was able to offer this under the NHS therefore no charge to the patient.

I also recall reading a book sometime ago telling that the cancer cells are quite weak and can possibly be prevented from multiplying out of control in the average person by heat as in saunas and infra red saunas etc therefore good as a preventative measure.

kellyt
kellyt
9 years ago

Re: 2010 TED talk where Dr. William Li introduced the crowd to “anti-angiogenesis therapy”… very cool. Kill blood supply, kill the cancer. Stop the blood supply from developing, stop the cancer from developing..

I read through this fascinating paper today that describes the mechanisms by which calorie restriction (CR) helps to fight cancer: http://www.cancerandmetabolism.com/content/1/1/10

Check these quotes out from the paper:

“Calorie restriction consistently and robustly decreases systemic leptin levels… Leptin… impacts angiogenesis…”

“Calorie restriction decreases chronic inflammation. The transcription factor NF-κB … is activated in response to … inflammatory molecules and is responsible for inducing gene expression associated with … angiogenesis.”

“PAI-1 is also involved in angiogenesis … Circulating levels of PAI-1 are consistently decreased in response to CR.”

Now consider:

In many ways, the ketogenic diet, when done correctly with the appropriate amount of protein, manipulates the exact mechanisms… Why?

Because the Keto diet mimics calorie restriction. It tricks the body into thinking that nutrients are scarce by keeping insulin, mTOR and leptin low… This puts the body into “maintenance and repair” mode – without starving you to do it.

Rosedale covers much of these concepts in this post: http://drrosedale.com/blog/2011/11/22/is-the-term-safe-starches-an-oxymoron/#axzz3CJOLVzQE

Keto diet – 2 birds, one stone.

Starve the cancer of it’s much needed glucose AND blood supply 😉

Fascinating.

Marc
Marc
9 years ago

Perhaps we should be looking at the rare, but regular occurrences of spontaneous remissions. Nothing cures cancer like natural phenomenon.

ashedwardsatl
ashedwardsatl
9 years ago
Reply to  Marc

A book was written about that very thing. As I recall an odd, unexplained fever preceded many documented spontaneous remissions. It was also noted that occurrences of spontaneous remissions have decreased … possibly due to supression of fever.

Susan
Susan
9 years ago

I took Metformin 500mg 1 x day for cancer prevention as I have a pre-cancerous condition and there is a good deal of cancer and vascular disease in my family—it completely wreaked havoc on my system. My arms and legs became numb, I got yeast and urinary tract infections, and muscle spasms and muscle pain all over my body. On the 12th day I almost went to ER as my arms were almost completely numb and felt as if they had weights tied to them and I got chest pressure, tightness and severe palpitations. I thought I was having cardiac arrest. I did not take last night’s dose and the numbness has subsided a bit. I am very disappointed as i was hoping to use this to avoid the fate of so many others in my family. Has anyone had these experiences on Metformin and did any adjustments help? Thank you.

Christopher Maloney, Naturopathic Doctor
Christopher Maloney, Naturopathic Doctor
9 years ago

Thanks for the article! In terms of tracking glucose intake and cancer, we have a prospective, seven-year study of patients who either follow conventional and alternative treatments or who follow those treatments and avoid all sugars. The results support the idea that cancer feeds directly on sugar. Here’s my blog post summarizing the study as well as a link to the study itself. http://alternativendhealth.wordpress.com/2014/05/24/should-cancer-patients-avoid-all-sugar/

Enrico DePaolis
Enrico DePaolis
9 years ago

I enjoyed reading this article. I too have been researching diet and also exercise effects on cancer patients. I have found that there are over 150 clinical trials in these areas and based on my findings I have created an online site just for cancer patients and those affected by cancer. It is just starting to launch and I hope to create the largest database on how exercise and diet affect cancers worldwide. Tim, I would appreciate any guidance you can provide on how I can make the site better and also if you or any of your oncology friends are interested in being a part of the advisory board. Please check out my site at http://cancer.fitness.

Bryan Haydukewich
Bryan Haydukewich
9 years ago

Yes, the compound 3bromopyruvate (3BP) developed at Johns Hopkins under Younghee Ko and Peter Petersen seems especially promising. If you recognize the later name, youll know that no man other than Petersen has held the torch of the metabolic mitochondial theory of cancer longer. Peter, you mentioned Seyfried, which has done some studies with deoxyglucose in conjunction with the ketogenic diet. Well 3BP is like deoxyglucose on steroids in its ability to inhibit cancer cell energy metabolism yet is less toxic. This compound even has Crick’s enthusiastic support (of Watson and Crick fame).

Give a quick search to “YH Ko 3BP” or “3BP cancer.”

Terry Sidhu
Terry Sidhu
9 years ago

Thanks for posting, I read Pete’s previous post before reading this one and it really helped build a solid level of understanding. I’ve been trying to wrap my head around cancer over the last few months, ever since my dad was diagnosed with Thymoma. The Doctors don’t have vasts amount of information on his type of cancer, and we’ve been looking into various types of treatment as the chemotherapy may not work effectively. Side note, i’m looking to hear from anyone who might have any information or experience with Thymoma, any insight would be much appreciated!

Pauline
Pauline
9 years ago

Tim, you will be awestruck after you watch Jorge Soto’s TED Talk on “The Future of Cancer Detection.” And if you can persuade Bryan Johnson watch it, he’d probably want to consider Soto’s team for his “Rewrite the OS” innovation funding to truly change the world.

Marc Theiler
Marc Theiler
9 years ago

Damn it Tim,

This just so happens to be a subject I’m researching, not so much specifically with cancer – more so energy systems, longevity, autophagy and the wild and wonderful mitochondrion. The keys to it all lie within the Mitchondrion. Since I’m already distracted this morning and have a shit ton of real world to complete, I cannot expand now, but I will later when the time allows the luxury. I’d like to review this post and content in order to “match up” with my “meat and potatoes”.

The next level of our “Health Revolution” is here, now.

Rhiannon Decker
Rhiannon Decker
9 years ago

Scrumptious read – I love the science of the body. Thank you!

April Capil
April Capil
9 years ago

Tim, what interests me the most (as a cancer survivor) is that all the conversations about curing cancer, preventing cancer, and treating cancer ignore the elephant in the room, which is that cancer can happen to anyone. It can happen if you’re a vegetarian, or a triathlete, or a smoker, or a 7 year-old. And what people who have never had cancer are really looking for in articles about preventions and cures, even well-thought out articles like this one, is really a kind of insurance against an uncontrollable, unpredictable world where bad things happen despite all precaution.

People like me, though – people who have been through the Hero’s Journey and come out on the other side – we know the truth: that cancer can happen no matter how many cups of green tea you drink, no matter how many push-ups you do or malt balls you stay away from. It’s what no one wants to hear, right? I see it in people’s eyes when they ask, “Did your doctor recommend a biopsy?” or “Do you have a family history?” or “Have you tried alkaline water?” We want to believe in a Newtonian universe where there is a cause and effect for things, because if there’s a cause and effect, if shit doesn’t JUST HAPPEN FOR NO GOOD REASON, then we don’t have to worry about our mothers and daughters and 22-year old brothers being taken away from us by the Emperor of All Maladies. Us humans, we have a weakness for math and magical thinking.

I have seen firsthand that there is no one strategy for fighting cancer. Some people live and some people die, and believe me, there is no logic in any of it. I can say that being a survivor means finding that place between blaming yourself for your illness and resenting the injustice of an unfair world – that place where survivors of war and rape and addiction can somehow imagine a future happiness, a happiness that manages a detente with the fear of a recurrence. This much I know.

Tim Ferriss, you of all people should know that prevention is all well and good, but survival is the better lesson.

Patrick J
Patrick J
9 years ago

I went on a ketogenic diet 12-months before I was diagnosed and possibly 6-months before a tumor started growing. Luckily mine was treatable but I have a 1% chance of it returning which would be catastrophic.

Obviously there’s no causation between these two things and it’s possible (but unlikely) that I had the tumor before. I am back on a ketogenic diet now in hopes I can lower my IGF1 levels and just be healthy.

One of my doctors was skeptical that I could lower my IGF1 levels by diet. That’s the worse part about this experience, the doctors’ knowledge is very specific and they have no answers of what I can do to prevent the 1% scenario.

Dr. N
Dr. N
9 years ago

However, I am a physician who can reverse (illegal to say “cure”) chronic diseases including metastatic terminal cancers. For the past past 44 years we have delivered an all natural treatment on over 100,000 patients successfully reversing their condition(s) completely by naturally regenerating new healthy tissue overcoming “incurable” diseases. The method regenerates new tissue through out the body to reverse diseases like blindness, heart disease, stroke, cancers including metistatic disease, diabetes type I and II and many others using bioelectrical energy and evidence based natural medicine. I would prefer to remain anonymous at this time due to the unwanted attention from the state board regulating my license under “scope of practice” and “standard of care” regulations. I do agree with the above article. It is aligned with my treatment protocols.

Jesse Freitag-Akselrod
Jesse Freitag-Akselrod
9 years ago

Hi Tim,

Thank you for this incredible article and for your effort to demystify cancer for us.

I am commenting here to share a (hopefully lasting) success story in slowing/stopping the progression of my mother’s cancer, compliments of your blogging.

I’d also love to get your (or anyone else’s) insights/pointers on our ongoing effort to stop keep my mother healthy.

For background: About 3 1/2 years ago my mother Eva (67) began experiencing severe anaemia, requiring blood transfusions every 3-4 weeks. At the same time, she was diagnosed with breast cancer and chronic lymphatic leukaemia (CLL) . The breast cancer was treated successfully and has not recurred; the CLL was deemed not necessary to treat.

The anaemic episodes continued, however. Numerous treating doctors have extended (then rescinded) various diagnoses, multiple myeloma, among them. The most recent diagnosis is “probable myelodysplastic syndrome (MDS)… and a possible immunological trigger.” We’ve heard from most of these doctors that “we don’t really know what she’s got, but luckily her anaemia is very isolated.” As such, some kind of mystery blood cancer.

In mid-JUN this year my mother then began a ketogenic diet. We became aware of the process of ketosis and the ketogenic diet after reading the fourhourworkweek/fourhourbody and doing some related research. Thank you Tim.

Her anaemia has improved significantly since then and she has not needed a transfusion for over three months now; her HB-levels had in fact increased to almost normal levels. On a more recent check-up, her HB-level had slightly fallen back again, however, so we’re redoubling our effort to find ways to keep the anaemia in check.

From this article, I gathered that slow-acting metformin is being used to check the glucose/insulin/IGF-1loop in thwarting cancer-promoting growth signaling and the Warburg effect.

In this vein, I’m wondering if alpha lypoic acid (ALA), may be a smart thing for my mother to supplement with? Or other insulin/blood sugar suppressing supplements?

I’ve also understood from Dr Rhona Patrick’s (excellent) two part series on cancer at foundmyfitness, that eating cruciferous vegetables is beneficial in DNA repair.

I’ve recommended Eva start eating lots of leafy greens. Should she also be supplementing with Magnesium/Calcium/K1 in pill form? Or anything else that would aid DNA repair?

Dr Patrick also highlighted Vitamin D as potentially beneficial, due to it’s anti-angiogenic properties.

Is there anything else Eva should be eating/supplementing with? For example supplements or foods that inhibit glutaminolysis?

Thank you for all of your help. We are very grateful for your insights and dedication.

Eva and Jesse

Boris
Boris
9 years ago

Tim & Peter. Greetings from my travels in Slovakia. Very interesting post thank you – we should probably eat less, and if eating weren’t so enjoyable I would be “eating – or rather not eating – my own dog food too” and fasting more often. Just to add another perspective on this, a friend of mine in LA just survived breast cancer and 2 years later appears symptom free after undergoing the traditional chemo treatment for it. She believes her successful treatment was in no small part due to the excellent medical advice she was given by her oncologist in Westlake, CA ( unfortunately, I can’t remember his name). He told her the following: the only common lifestyle trait he had managed to pick up on in all his patients who came to him with cancer is that they all took multivitamins (!!!), but nevertheless appeared to have low vitamin D levels. When asked what was the single most effective way to guard against cancer, he said he believed it was to increase your levels of vitamin D – ideally through careful sun exposure and if this was not possible, then through taking vitamin D supplements. I noticed this view is also shared by Dr Mercola on his excellent website.

Dana
Dana
9 years ago
Reply to  Boris

I take a multivitamin, but I am very picky about what’s in it. I have a copy of a mutated MTFR gene so I make sure to get methyl folate and methyl B12. I also make sure the minerals are all chelate form to avoid ion-channel conflict (why take it if you’re just going to poo it away?). I also take additional A (NOT beta carotene–if you’re gonna get that, eat it in food), D3, and K2 (a complex of both mk-4 and mk-7) along with it. Anyone taking Centrum is asking for bad health; the folic acid alone will get you into lots of trouble if you don’t know your MTFR status.

kapie9969
kapie9969
9 years ago

I have a good book Killing cancer by Jason Winters. Laetrile is a big part of killing cancer. Bitter almonds and apricot kernels is what this is made from.

His book makes sense.

Pamela Baergen
Pamela Baergen
9 years ago

My sister is currently undergoing something called the Gerson Method. She has a particularly fast-acting, rare cancer that can’t be detected until it metastasizes. Basically, when it’s detected – she’s only got a few months to live. The Gerson Method was pioneered in the 40s, I believe, and is, of course, illegal in the US. My sister went to Mexico for an initial 2 weeks of “treatment.” This mostly consisted of detoxing, diet, etc. She is currently finishing up her first year of treatment and starting her 2nd. As her doctors (US) have said: without Chemo and Radiation treatment, she should be riddled with cancer and quite frankly dead right now.

Alex B
Alex B
9 years ago
Reply to  Pamela Baergen

Ms Baergen and all who have loved ones with cancer who have posted on this article, please be cautious regarding “alternative treatments” for cancer therapy. A sad truth is that people will undergo desperate measures in such profoundly difficult situations. A sad truth is that MONETARY GAIN propels individuals to take advantage of people in desperate times.

Please review the website, http://www.quackwatch.com, which attempts to uncover such nefarious and/or unfounded practices. Also review this specific article describing the Gerson Method: http://www.quackwatch.com/01QuackeryRelatedTopics/cancer.html#gerson.

As an oncologist, I have seen far too many folks suffer from these misadventures; they lose money (often exorbitant amounts), lose time away from family traveling to far off places, and sometimes suffer devastating complications from unproven therapies. My prayers go out to those battling cancer and to their families and loved ones.

Dana
Dana
9 years ago
Reply to  Alex B

Quackwatch has a hardon for dissing low-carb diets. As it turns out, they’re wrong. I’ll keep my own counsel on whether I think someone is a quack, although I certainly agree Gerson was one. If his methods work for anyone it’s because they were eating such a phenomenally high amount of sugar prior to taking on his diet that even switching over to all that fruit was cutting their carbs. In terms of weight loss rather than cancer treatment, low-fat diets can work for the same reason if they are also low-calorie, because cutting those calories means cutting carbs too. Don’t be deceived. It may not be enough. People have died on Gerson. Johnny Gunther was a famous example.

JJ Boudy
JJ Boudy
9 years ago

Interesting and informative post.

Related to the subject of cancer and overall health in general, what do you think about CBD oils?

Forgive me if I’ve missed your stance on cannabis somewhere; I think remember reading or maybe hearing, that you don’t smoke, but I am curious as to what you think about CBD oil and the other more or less, constituents of the cannabis plant.

Thank you

Shasta Marie McBride
Shasta Marie McBride
9 years ago

Dear Tim, Thank you for posting this article. My father passed away from a rare cancer called hemangiopericytoma last year. He was 62 and lived a very healthy and stress free life on Kauai. The Mayo Clinic, Anderson, and UW cancer centers could not diagnose what he had other than it was in the 1% of 1% of rare cancers caused by angiogenesis. I’ve watched Dr.Li’s TED talk many times and incorporated much of his antiangiogenic diet recommendations. I also drink a lot of tea so have enjoyed blending and mixing the teas.

I am wondering how you know to mix green sencha with white jasmine dragon pearl. In Dr.Li’s talk at 13:20min I miss where he says it’s white jasmine dragon pearl and only hear jasmine dragon pearl. The green jasmine is much more readily available than the white variety. Does he specify white jasmine pearl or have you verified this combination elsewhere? Any extra information you have here is greatly appreciated. Thank you and Aloha, Shasta

Dana
Dana
9 years ago

I can tell who didn’t read this article by who comes in here extolling the virtues of high-sugar “natural fruit and veggie” diets. That’s not what the article says at all. And there is zero evidence that meat causes cancer or makes it worse, and even the evidence that processed meat does that is pretty shaky. (I’m not sure they controlled for the fact that many people eating processed meat also have bad health habits otherwise–and processed meat often contains SUGAR, which as this article outlines is probably behind a lot of cancer in the first place.)

Know where I first heard about Gerson? John Gunther’s Death Be Not Proud. Because they tried it with his son Johnny. Johnny didn’t make it.

d
d
8 years ago
Reply to  Dana

Dana,

No treatment is 100%. I’ve had family die under chemo treatment, that doesn’t mean it should be completely discounted. Gerson Method is completely valid and there are more success stories than losses. Not to mention, a much better quality of life during treatment than chemo.

-d

Michael
Michael
8 years ago

Well done Tim. I suggest that you take on the DMU-212 Stilserene project as an adjunct to your experience. We have been eating this fruit extract for 14 years. We have 562 Members at the Cancer Phytotherapy Service run by the ResQ Club at Hastings UK. Just click onto Professor Gerry Potter and Professor Danny Burke’s and read up on their work.

Samantha Reed
Samantha Reed
8 years ago

Wow !!

Adam Ball DC
Adam Ball DC
8 years ago

Hey Tim! I’m normally interested in prevention before issues show up, but I had the chance to listen to a great presentation about a novel approach to cancer treatment that is gaining some serious traction AND makes good sense (though reminds me a little of I am Legend) http://www.cheori.org/en/newsreleases?newsid=394

Alfonso Fernández
Alfonso Fernández
8 years ago

Thank you SO much for this post,Tim!

Mike
Mike
8 years ago

Has anyone heard of the work being done by Ido Bachelet and Shawn Douglas on targeted therapeutics and nanorobotics? The hope is that it allows potent chemo drugs (or anything that would fit inside the compartment) to be administered directly at the cell level by using programmable nano containers that can talk to each other, without taking out healthy cells, only cancerous ones. It really is fascinating stuff. They are both featured at solveforx.com: https://www.solveforx.com/profile/5682747733442560

Jaideep Gill
Jaideep Gill
8 years ago

Very nice article Tim, I lost my mom to breast cancer so it hits home. I saw the VICE documentary on hbo, how diseases like measles can be programed to infiltrate cancer cells and the dormant immune system suddenly activates to destroy cancer cells and the measles disease. I thought that was amazing and it seemed very promising in the documentary. I do truly believe its allot more simpler to cure than these types of therapies but Shane Smith (founder of Vice) went as far to say that first this therapy could be considered as a cure. Here is the link for anyone who can watch it on hbogo: http://www.hbo.com/vice/episodes/03/00-vice-special-report-killing-cancer/index.html

d
d
8 years ago

Tim,

You mention that, “To date, no studies in humans are evaluating the therapeutic efficacy of glucose and/or insulin reduction via diet.” Why don’t you count the work of Dr Max Gerson or the Gerson Institute? That’s pretty much all they do and with great success. Just wondering…

-d

Dr Green
Dr Green
8 years ago

Hi Tim,

Thanks for sharing this, there is also a New article of Poff et al. Out there you might wanna check out

http://www.ncbi.nlm.nih.gov/pubmed/26061868

Dan Lawrence
Dan Lawrence
8 years ago

Great article! but no mention of Cannabis, what are your thoughts on the relatively recent ‘buzz’ regarding Cannabinoids being a direct cancer cell destroyer ?

Larry
Larry
8 years ago

Tim – So there’s definitely a lot of info here. But why should this page become the living resource, when this page: https://en.wikipedia.org/wiki/Cancer should be that resource or perhaps even this one: http://www.webmd.com/cancer/default.htm

I’m sorry to ask the obvious question here, but why would you want to direct people to this blog instead of more comprehensive sources for cancer info?

Peter
Peter
8 years ago

Great work Tim – lost a family member to pancreatic cancer 2y ago. Ever seen that video from a TEDx talk?

http://youtu.be/h2ynTDjlk7k

Keep up with making our lifes longer, more enjoyable & meaningful.

Matti Anttila
Matti Anttila
8 years ago

Wonderful resource: NATUROPATHIC ONCOLOGY. AN ENCYCLOPEDIC GUIDE FOR PATIENTS AND PHYSICIANS. Seems quite comprehensive to this lay-cowboy. Love and laughter, Matti Anttila Certified Laughter Yoga Teacher and author of THE ZEN OF JOY.

Viet
Viet
8 years ago

I have a family member just recently diagnosed with the 4-stage esophagus cancer, with metastasis to stomach and colon. We are trying everything we can, i.e. ketogenic diet, hyperbaric treatment, anti-angiogenesis, essiac etc. Recently we have stumbled upon this interesting research from University of Washington and have added it to our arsenal of weapons against Cancer. It is a substance called artimisinin. It has already been established as the major malaria drug, and now has been identified in in-vitro environment as killing cancer cells. If you are looking for more help, it is worth reading http://www.washington.edu/news/2011/04/04/high-dose-of-oxygen-enhances-natural-cancer-treatment/

moneyblog442
moneyblog442
8 years ago

Great stuff! As the #4 child in my family, I realize that 1, 2 and 3 have all had cancer. My new hobby is preventing cancer, and this is a tremendous resource.

Patrick F

Janell Kaplan
Janell Kaplan
8 years ago

Tim, thank you for this excellent and important post—I was diagnosed with and treated conventionally for Hodgkin’s lymphoma in 1999. The late effects of treatment were harder on my health than the cancer ever was. Thankfully, I happened on similar information to what you’ve shared here when CT/PET scans showed possible recurrence/ secondary cancers in 2004 and in 2007. There are more than a few ways to prevent/ treat cancer without harming your health in the process. Thank you for using your forum to have this life-saving discussion.

Joe
Joe
8 years ago

This seems to imply that a ketogenic diet and/or intermittent fasting should have an anti-cancer effect. Did I interpret that correctly?

Jeff
Jeff
8 years ago

Yep Tim . . . Otto Warburg is the key. Alkaline forming foods. Killing cancer without killing other cells is actually easier than you think. They’ve been doing it in non-chemo subsidizing companies for years. [Moderator: links removed]

Bill Piazzetta
Bill Piazzetta
8 years ago

Here in Brazil we’ve been having some controversy surrounding a substance synthesized by a researcher from the University of São Paulo which he claims (along with several patients) cures cancer. They distributed the pills for free until the government intervened because there weren’t enough tests to prove it actually worked. I think some guy even paid out of his own pocket to have the pills produced (I remember reading they cost around 10 cents a pill) and distributed them, and was sued by the government. The patients went to court and managed to get access to the medication again. Here are a couple of links about it (in English):

http://www.poandpo.com/in-sickness-and-health/brazil-to-test-controversial-cancer-treatment-15-11-2015/

http://www.nature.com/news/brazilian-courts-tussle-over-unproven-cancer-treatment-1.18864?WT.ec_id=NATURE-20151126&spMailingID=50106434&spUserID=OTE0NDIzNDAxNzMS1&spJobID=803457227&spReportId=ODAzNDU3MjI3S0

And here’s the Wikipedia page on the substance (in Portuguese, the English version has practically no information at all):

https://pt.wikipedia.org/wiki/Fosfoetanolamina

Jeff
Jeff
8 years ago
Reply to  Bill Piazzetta

Thank you Bill!

resqclubhastings
resqclubhastings
8 years ago
Reply to  Bill Piazzetta

Hi, Tim,

Please include the role of CYP1B1 in metabolising multi fruit essence such as salvestrols (phytoalexins) fruit colouring molecules ito cytotoxins such as piceatannol which disintegrates the cancer cell wall. CYP1B1 is only expressed after mutation thus is found only in cancer cells. Normal cells are unaffected. This phytotherapy works fantastically dealing with metastatsis too. We’ve been looking after 650 folk since July 2000.

More information in PDF “Delivery from Cancer” [Moderator: email address removed]

Just apply. Cheers.

Michael Cleary

HonSec

Cancer Phytotherapy Service (the ResQ Club)

Hastings UK

craig
craig
7 years ago

have just watched an interesting story on australian science tv show ‘catalyst’. Seems to be very strong evidence for benefits of a targeted exercise during cancer treatment. Australian scientists apparently will be the first to release their findings. Scientists in sweden and denmark are also doing similar research into the benefits of targeted exercise before, during and after chemo. Seems like this approach may well become the norm in the near future? Transcript here if anyone who wishes to delve further: http://www.abc.net.au/catalyst/stories/4459555.htm

mark steinman
mark steinman
7 years ago

Tim, does your diet include lots of cooked tomato sauce for the lycopene? (from Dr. Li’s suggestion)?

Hanna
Hanna
7 years ago

My partner found out she has a brain tumour (glioblastoma). She and I were actually just talking about anti-angiogenesis and I sent her Dr. Li’s ted talk. I’m thinking about talking to her about the ketogenic diet but I don’t know how effective it could be for her tumour. If anyone has any additional links or reading besides the ones Tim posted, I’d be really appreciative to have them shared with me. Thanks!

Chris
Chris
7 years ago

Hey Tim,

Great article – I was watching a show last night called Catalyst (ABC Australia) – they were highlighting the benefits of using targeted exercise to beat

Cancer. Really interesting watching.

http://www.abc.net.au/catalyst/stories/4459555.htm

Timea
Timea
7 years ago

Great stuff!

Also, Ty Bollinger, the Truth about Cancer.. Have you talked to him yet? He has done and interviewed many alternative therapists over many years.. Fascinating!

Abraham
Abraham
7 years ago

I want to offer up Dr. Tony Jiminez who runs hope4Cancer in Mexico. He has been fighting cancer with diet and other forms of non chemo protocols. He is a potential resource for anyone looking for an alternative to traditional treatments.

Hope4Cancer.com

Abraham
Abraham
7 years ago

High Dose Ozone treatments are another weapon to potentially be used against cancer or as a preventative measure. Dr. Howard Liebowitz tells the story of a patient who was cured of stage 4 metastatic breast cancer.

[Moderator: link removed]

Tim keep up the great work.

Ryan
Ryan
7 years ago

You should check out the story of an incredible cancer survivor named Andrew Abraham. He beat cancer as a teenager with a 15% chance to live. Ended up starting a very successful company called Orgain that makes Protein Powders and Nutritional Shakes.

chadrissanen
chadrissanen
7 years ago

Outstanding Tim! And a real eye opener. Thank you for sharing this information.

Tim
Tim
7 years ago

I’m late to this subject. 4months ago I tried Dom’s fasting strategy but not yet the ketogenic diet. I did 2 40 hour fasts a week apart. After each fast I got a huge gout attack in my right big toe. I need a recommendation on how to come out of a fast so I don’t get the gout attack.